Kidney damaging drugs
Nephrotoxic drugs are characterized as having the potential
to harm the kidneys. The kidneys may suffer immediate harm from certain
medications. Some of these drugs moderately impair kidney function, while
others can seriously harm the kidneys. The possibility of kidney impairment is
influenced by your own health and any additional medications you're taking. You
might wish to discuss the benefits and drawbacks of these medications with your
doctor if you have even a minor case of renal failure.
1 . Vancomycin
The IV antibiotic vancomycin is frequently administered to
patients who have severe methicillin-resistant Staphylococcus aureus (MRSA)
infections. While treating your illness, your doctor will carefully monitor
your kidneys for any damage because this medicine might harm them and lead to
acute interstitial nephritis (kidney inflammation) in some patients.
2.
NSAIDS
a consequence of their extensive usages, NSAIDS, or nonsteroidal anti-inflammatory medicines, such as ibuprofen (Advil, Motrin), and naproxen (Aleve), top the list of substances that harm kidneys. NSAIDs are used to treat a wide range of ailments including fever, rheumatoid arthritis, menstrual pain, and inflammation; however, they can also lower the quantity of blood flow to the kidneys, raising the risk of kidney damage or failure. Even more, people are at risk when taking NSAIDs: those with heart failure, liver illness, or past renal issues.
Try to use these drugs as little as possible, for the
shortest amount of time, at the lowest effective dose.
3.
Diuretics
Water tablets, or diuretics, are prescribed to treat edema,
glaucoma, and high blood pressure, among other diseases, but they carry some
hazards, just like any other prescription. Hydrochlorothiazide, furosemide, and
spironolactone are a few of the most well-known diuretics. Acute kidney damage
is a danger that is connected to them.
4. ACE
inhibitors
Both favorable and harmful effects on the kidneys can be
attributed to ACE inhibitors. These include drugs with names that frequently
finish in "-il," such as lisinopril, enalapril, and ramipril. ACE
inhibitors are often prescribed medications for heart failure and excessive
blood pressure.
5.
Iodine radiocontrast
Iodinated radiocontrast, despite seeming like a technical
phrase, refers to any contrast dyes used in diagnostic testing, like a CT scan.
Within 24 to 48 hours following an IV contrast injection, iodinated
radiocontrast chemicals are one of the most frequent causes of kidney
impairment among hospitalized patients.
Since ACE inhibitors are processed by the kidneys, there is
a chance that taking them could harm your kidneys, especially if you're
dehydrated, which is frequently the case in those with pre-existing renal
issues like chronic kidney disease. If you require an ACE inhibitor and are
more prone to experience kidney damage,
your doctor will likely prescribe a modest dose and may ask
you to undergo regular blood creatinine tests to check on the condition of your
kidneys.
ALSO READ: Tramadol Side Effects on Kidney and Liver
6.
Jardiance
A diabetes drug called Jardiance has been shown to seldom
result in kidney failure, although it may protect the kidneys in diabetic
patients who use it. Furthermore, Jardiance interacts with other nephrotoxic
medications (drugs on this list), which increases the risk of toxic renal
consequences. Jardiance also has diuretic effects. Again, it's extremely
unlikely, but it can happen.
7.
Antibiotics with aminoglycosides
Even at modest doses, aminoglycoside antibiotics are known
to harm the kidneys. High-risk groups include people who have taken these antibiotics
for a long time, are dehydrated or have chronic kidney disease. Neomycin,
followed by gentamicin, tobramycin, and amikacin, is the most poisonous
aminoglycoside. The least hazardous drug is streptomycin. Although these drugs
are frequently used in hospitals, it's still crucial to keep them in mind!
8. HIV
medicines and antiviral medicines
You may be at an increased risk for kidney illness if you
take some antiviral HIV drugs, which have been related to chronic kidney
damage. Both Reyataz (atazanavir) and Viread (tenofovir) have been demonstrated
to cause acute renal damage.
9.
Zoledronic acid
Although it is commonly used to treat osteoporosis,
zoledronic acid (Zometa, Reclast) is known to induce kidney damage and renal
failure. The IV drug Zometa is crucial for the treatment of metastatic bone
cancer, yet it is known to have the potential to harm kidney function.
10
Foscarnet
Foscarnet, which is also administered intravenously, is a
rarely prescribed medication that cures viral infections in people with
compromised immune systems. Your doctor will carefully check your kidney
function if you need it because it can be quite damaging to the kidneys.
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