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 Is tramadol bad for your kidneys or liver?

A medication called tramadol may be prescribed by your doctor if you experience either short-term pain from a procedure or long-term chronic pain. Adults who experience both acute and chronic pain are prescribed tramadol.

Like many medicines, tramadol can have negative side effects, and you may have heard that it can harm the kidneys or liver. Learn more about tramadol's usage, effects, and potential for addiction as you continue reading to find out if this is the case.

What exactly is tramadol?

An opioid drug called tramadol is prescribed to adults for mild to moderately severe pain. Tramadol is specifically a synthetic drug, meaning it is created in a lab. Additionally, it is used off-label for restless legs syndrome and early ejaculation.

The drug sold under the brand names Ultram, Ultram ER, and Conzip is known by its generic name, tramadol. As a generic and under the brand name Ultracet, it is also offered in conjunction with acetaminophen.

There are instant and extended-release formulae, but the latter should only be used for brief periods of time—no more than a week at a time. Both formulae are offered for purchase as capsules.

Is it safe to use Tramadol?

Tramadol is a class IV opioid, according to the Food and Opioid Administration (FDA), which implies it has some potential for addiction or dependence but is still permitted for medical usage.

Tramadol and opioid risks

The federal regulatory body has issued various cautions about tramadol, including:

  1. Tramadol shouldn't be used by children under 12 due to a contraindication, the FDA's greatest caution.
  2. a warning against giving tramadol to youngsters under the age of 18 to manage pain after having their tonsils or adenoids removed.
  3. Tramadol should not be used by adolescents aged 12 to 18 who are obese, have obstructive sleep apnea, or have a long illness.
  4. that breastfeeding mothers shouldn't take tramadol
  5. Even if tramadol is recommended for medicinal purposes, users nevertheless run the danger of developing an addiction, as is the case with all opioids.

Tramadol should be used exactly as recommended to help lower the chance of dependence. Do not crush, chew, break, or dissolve tramadol capsules, nor should you take them more frequently than your doctor has prescribed. If you take too much tramadol, you could experience an opioid overdose, which is potentially lethal.

Does tramadol damage the liver or kidneys?

Your liver breaks down tramadol during the metabolization process. This implies that there's a possibility it could harm the liver. However, if you use tramadol at the usual, recommended levels, liver damage is not frequently experienced. If they do happen, they often don't last long and get better on their own.

Your doctor will do a baseline liver function test before you begin taking tramadol since there is a small chance that it could harm your liver. They will continue to check your liver function if you take tramadol for an extended period of time to make sure everything is alright.

Although tramadol does not directly harm your kidneys, it can be risky for those who have a chronic renal illness.

If you have liver or kidney disease, let your doctor know. They might decide to give you a new medicine, a lesser dose, or spread out your doses.

If you use high dosages of tramadol, liver, and kidney damage are both more likely to occur. Additionally, tramadol overdose might result in abrupt liver or renal failure. That's still another justification for merely utilizing tramadol as directed.

ALSO READ: Top 10 Drugs That Can Cause Kidney Damage

What does tramadol do to your body?

You could feel sleepy or drowsy after taking tramadol. Your respiration and movements may both slow down as a result. As a result, you shouldn't combine tramadol with benzodiazepines, alcohol, or other drugs that cause the central nervous system to become depressed.

Once you get up from lying down, it can also make you feel woozy or lightheaded, so take it slow and wait a little while before standing.

Tramadol also has other side effects such as:

  1. Headache
  2. Nervousness
  3. Tense muscles
  4. Constipation
  5. Changes in mood
  6.  Body shaking
  7. Heartburn
  8. Indigestion
  9. Oral aridity

To ensure you don't have any harmful side effects if you take tramadol for a prolonged period of time, your doctor should continue to check your blood pressure, respiratory system, and mental status.

Tramadol withdrawal symptoms may occur if you suddenly stop taking the medication. Always with your doctor before stopping tramadol use, particularly if you've been doing so for a while. You can taper off with their aid.


Adults with moderate to severe pain may benefit greatly from tramadol, but there are some restrictions and precautions to be aware of. In particular, after having their tonsils or adenoids removed, if they are obese, or if they have sleep apnea, children under the age of 18 should not take tramadol. Tramadol usage is also not advised during pregnancy.

Tramadol probably won't harm the liver in the majority of users. If it occurs, the harm will probably be minimal and disappear on its own. Tramadol, however, poses a risk to those who already have liver or kidney problems. If your doctor prescribes tramadol despite your liver or kidney issues, discuss your options with them. You might get another prescription from them.

Keep learning while staying healthy!

Pay attention to the advice we've provided if you want to achieve your greatest level of health and fitness. We are committed to providing top-notch, fact-based services that have an impact on your general well-being. We have assembled a team of professionals to develop educational materials on a variety of health-related subjects. We make an effort to educate you so that you can lead the most fulfilling life imaginable. There are sections with recommendations for sleep hygiene and the most recent news.


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