Women health

Best at-home male fertility test

Men may utilize an accurate and convenient test to determine the fertility of their sperm, according to researchers.

Infertility affects 45 million couples globally, according to estimates.

The male partner is responsible for about 40% of these situations.

In the United States, one out of every eight couples is unable to conceive, with male infertility accounting for a third of these cases.

Infertility diagnosis is currently costly and can only be performed in a clinic or hospital.

However, a team of researchers from Brigham and Women's Hospital (BWH) in Boston, in conjunction with Massachusetts General Hospital (MGH), have developed a new, low-cost, and easy-to-use technique for identifying male infertility.

The new device, which has yet to be named, is controlled by a smartphone and may be used at home.

Researchers claim that the new technology evaluates and analyses sperm quality using motility and sperm concentration parameters, ultimately determining infertility with a 98 percent accuracy.

The research team that designed and tested the device was led by Manoj Kanakasabapathy. Science Translational Medicine reported the research findings.

How the device driver works

The sperm analyser consists of an optical attachment that links to a smartphone as well as a device that users can put a sample of their sperm into.

A disposable microchip with a capillary tip is used in the sperm sample device.

The software walks users through each step of the testing procedure. The total sperm count is also measured using a weight microscale that is wirelessly connected to the smartphone.

Hadi Shafiee, Ph.D., a co-author on the paper and a primary investigator in BWH's Division of Engineering in Medicine and Renal Division of Medicine, highlighted the team's motivation:

"We wanted to find a way to make male infertility testing as easy and economical as home pregnancy tests," he explained. "Men are required to deliver semen samples in these hospital rooms, a situation that frequently causes them stress, embarrassment, pessimism, and disillusionment. Clinical testing are now laboratory-based, time-consuming, and subjective. This test is low-cost, quantitative, and extremely accurate, and it takes less than five seconds to evaluate a video of an undiluted, unwashed semen sample."

Accurate user-friendly device driver

Kanakasabapathy and his team gathered and examined 350 clinical semen samples from the MGH Fertility Center to assess the device's accuracy.

The World Health Organization (WHO) defines normal sperm concentration as more than 15 million sperm per milliliter, and normal motility as more than 40% ability to transport sperm.

According to the researchers, the device determined infertility with 98 percent accuracy based on these parameters.

The researchers also wanted to see how easy the device was to operate, so they had both trained and untrained people use it.

More than 100 sperm samples were properly classified as viable or infertile by a total of ten users with no training.

Applications of the new device driver

The new tool, according to the researchers, will benefit a wide range of people.

Men who have had a vasectomy can use the home-based device to track their sperm for up to six months after the procedure. Patients who have had a vasectomy are currently needed to visit a urologist on a monthly basis to ensure that the procedure was effective, but the new gadget may make this unnecessary.

The novel device might potentially be utilized as a point-of-care testing tool, meaning it could be used not only at the patient's home, but also in the hospital or other settings.

Finally, the authors suggest that the gadget may be used to test animal fertility.

Dr. John Petrozza, research co-author and head of the MGH Fertility Center, adds, "Bringing point-of-care sperm testing to consumers or health facilities with limited resources is a true game changer." "More than 40% of infertile couples struggle to conceive due to sperm abnormalities, and this advancement will enhance access to fertility treatment." [...] We have truly succeeded in creating a product that will benefit a large number of people."

The new device is still simply a prototype, but once the researchers have completed additional testing, they will submit an application to the US Food and Drug Administration for approval.

YOU CAN ALSO READ:Food That Kills Sperm in the Men Body

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