Women health

 Is diabetes transferable from husband to wife?

A recent study published in the Journal of Experimental Medicine raises the possibility that type 2 diabetes is contagious and spreads from person to person.

Diabetes Type 2

The pancreas generates insulin, a hormone, to transfer glucose (also called blood sugar) into energy. Individuals with diabetes frequently need to monitor their blood sugar levels and administer insulin injections into their bodies on a regular basis because they can't make enough insulin or their bodies don't respond to it. Type 2 diabetes–the most prevalent kind of diabetes, is also termed adult-onset diabetes, which indicates it was acquired.

Type 2 diabetes affects more than 420 million people globally, and the causes are still mostly understood. It has been connected to being overweight and/or consuming excessive amounts of glucose, but not everyone who is overweight and consuming excessive amounts of sugar develops the disease.

According to a recent study by scientists at the University of Houston, type 2 diabetes is related to a class of contagious neurodegenerative disorders known as "prion diseases."

Type 2 diabetes and a class of transmissible neurodegenerative disorders known as "prion diseases" are comparable, according to a recent research study carried out at the University of Houston.

The link between "Mad Cow" and Creutzfeldt-Jakob disease

The most well-known proton diseases, often referred to as transmissible spongiform encephalopathies (TSEs), are the so-called "mad cow disease" and its human analog, Creutzfeldt-Jakob disease.

It has been estimated that up to 80% of individuals with type 2 diabetes also have a buildup of what are known as "misfolded islet amyloid polypeptide proteins" (IAPP). IAPP cells develop through a process known as folding, and it is believed that improperly folded IAPP harms the beta cells in the pancreas, reducing the body's capacity to generate the insulin required to lower blood sugar levels.

The discovery is important because it supports the theory that misfolded prion proteins are also responsible for TSEs. The study is far from conclusive, but if verified, it might alter the way scientists seek a possible treatment for type 2 diabetes.

The different diseases that exist

Spontaneous, inherited, and acquired prion disorders are the three types. Spontaneous diseases develop for no apparent reason and are called sporadic diseases. We can link a defective gene to inherited prion disease. An operation, a blood transfusion, or a foodborne sickness can all cause prion diseases to spread. Human Creutzfeldt-Jakob disease and related disorders are believed to occur almost exclusively sporadically.

The transmission of mad cow disease occurs when healthy cows consume the tissue of a sick cow. The findings do not point to diabetes being contagious in the sense of a cold or flu but rather point to the possibility that blood transfusions, organ transplants, or contaminated food could spread the illness.

In the most recent investigation, scientists injected mice's pancreases with misfolded IAPP. According to the study, type 2 diabetes signs appeared in mice just a few weeks after IAPP injection. The mice experienced beta cell loss and elevated blood sugar levels.

When a prion-like mechanism is discovered in IAPP to produce diabetes, it may be possible for diabetes to be acquired in addition to hereditary or sporadic. It's also possible that IAPP cells speed up diabetes progression.

Researchers warn that the findings are preliminary but speculate that they may pave the way for new lines of inquiry into the origins, treatments, and prevention of type 2 diabetes.

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